NFL odds and opening spreads for Week 13 betting

Thanksgiving Day offers NFL bettors an early start to their betting card with three games on tap.

The San Francisco 49ers are 5-0 SU in their last five home games against the Seattle Seahawks and they will try to continue that winning trend this Thursday night hosting their NFC West rivals at Levi's Stadium.

San Francisco is a 1-point home favorite according to sportsbooks monitored by OddsShark.com. While the 49ers have enjoyed SU home success against Seattle, the Seahawks own a 6-0 ATS edge over the last six games in this series including a 2-0 ATS record in their last two trips to San Francisco.

The spread isn't likely to come into play in this one with Seattle only getting one point on the road, and the match will surely impact NFC West lines and Super Bowl futures odds.

Chicago visits Detroit in the early game before Philadelphia heads to Dallas later in the afternoon on Thanksgiving leading up to Thursday night's game.

Chicago is 1-6-1 ATS in its last eight games against Detroit including an 0-4 ATS record in its last four trips to Detroit. Detroit is a 7-point home favorite over the Bears while the Cowboys are a 3-point favorite hosting the Eagles.

The AFC playoff picture is completely up in the air with five teams sitting at 7-4 SU and fighting over two Wild Card spots. That picture could become a bit clearer this Sunday after the San Diego Chargers visit the Baltimore Ravens.

Something has to give in this game as the Chargers are 10-3-1 ATS over their last 14 games as a road underdog and the Ravens are 9-3 ATS in their last 12 games as a home favorite. Baltimore is favored by 5.5 points on the Week 13 NFL betting lines.

Denver heads to Kansas City to take on the Chiefs in a game that could help decide AFC West supremacy. The Broncos are a perfect 10-0 SU and 9-1 ATS in their last 10 road games against AFC West opponents. Kansas City on the other hand is 6-15 ATS in its last 21 divisional home games. The Broncos are a 1.5-point road favorite.

On Monday night, the Miami Dolphins are a 5.5-point road favorite visiting the New York Jets. Miami is 5-1 SU and ATS in its last six games against the Jets according to the OddsShark NFL Database, and the total has gone UNDER in each of the last four games in this series.

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